Notice of the Opening of Haneda Packaging Center
–Strengthening the one-stop supply chain through group synergy–

TOHO HOLDINGS CO., LTD. (Headquarters: Tokyo; Representative Director, CEO and CFO: Hiromi Edahiro, hereinafter “TOHO HOLDINGS”) is pleased to announce that its subsidiary involved in pharmaceuticals manufacturing and sales business, KYOSOMIRAI PHARMA CO., LTD. (Headquarters: Tokyo; President and Representative Director: Yasuyuki Kumada hereinafter ” KYOSOMIRAI PHARMA “), will open a secondary packaging facility for pharmaceutical products, the Haneda Packaging Center, within the same facility as the high-function logistics center TBC DynaBASE as follows:

1.Purpose of Establishment of Haneda Packaging Center

TOHO HOLDINGS is a corporate group active in the medical, nursing and healthcare fields, engaged in pharmaceutical wholesaling, dispensing pharmacy, manufacturing and sales of pharmaceuticals, and development and provision of customer support systems under the corporate slogan “Total Commitment to Good Health”. TOHO HOLDINGS also proactively promotes initiatives for regional medical collaboration, nursing and home care. In line with its social mission of providing a stable supply of pharmaceuticals, the TOHO HOLDINGS Group aims to continue to be a company that is needed by society by contributing to the maintenance of the healthcare delivery system through high-quality logistics, and to establish a firm position as an indispensable player in the distribution of pharmaceuticals in Japan through the handling of specialty products, the market for which is expected to expand.
KYOSOMIRAI PHARMA is, as a pharmaceutical manufacturing and sales subsidiary of TOHO HOLDINGS, engaged in the sale of generic drugs, contract manufacturing and development support of injectable drugs, etc. By pursuing opportunities to expand the CDMO (contract development and manufacturing organization) business in the future, we will strengthen the pharmaceutical wholesaling business by expanding our full-line services for specialty products and enhance the Group’s profitability.
Based on the above business strategy, we have decided to open the Haneda Packaging Center as a secondary packaging facility for KYOSOMIRAI PHARMA’s prescription pharmaceuticals in the same facility as TBC DynaBASE, a highly functional logistics center. The Haneda Packaging Center will be equipped with facilities mainly for inspection, packaging, and storage of vial products containing cryogenic or antibody drugs. Taking advantage of its location near Haneda Airport, we will aggressively pursue contract opportunities from not only domestic pharmaceutical manufacturers but also overseas ones that do not have similar facilities in Japan. In addition, by integrating the CDMO, manufacturer warehouse, and wholesale warehouse functions within the same facility, we will establish an efficient one-stop supply chain. Furthermore, by reducing the vibration risk and achieving the advanced temperature control required for specialty pharmaceuticals and orphan drugs, we will contribute to the prompt and stable supply of pharmaceuticals to medical institutions and patients.

2. Overview of Haneda Packaging Center

Location: DynaBASE within Keihin Truck Terminal, 2-1-1 Heiwajima, Ota-ku, Tokyo, Japan (5th floors of DynaBASE)
Total floor space: 1,598 square meters
Product lines: Prescription pharmaceuticals
Scheduled operation: September,2025

3.Characteristics of Haneda Packaging Center

(1) Realization of one-stop supply chain through group synergy
By integrating KYOSOMIRAI PHARMA’s Haneda Packaging Center and the logistics functions of the pharmaceutical wholesaling business within the same facility as TBC DynaBASE, the series of flow from pharmaceutical manufacturing and sales to pharmaceutical wholesaling will be realized in a one-stop manner, creating an efficient supply chain.
(2) Secondary packaging facilities for prescription pharmaceuticals located in the vicinity of Haneda Airport Taking advantage of its convenient location near Haneda Airport, we will realize labeling, packaging, and storage of domestic products as well as imported products from overseas.
In addition, KYOSOMIRAI PHARMA’s Shinagawa Plant will be used as an external testing institution to handle contract development and pre-marketing testing.
(3) State-of-the-art production equipment for secondary packaging (inspection and packaging) to be installed The Haneda Packaging Center will be equipped with state-of-the-art inspection and packaging equipment for secondary packaging, including in-liquid foreign matter detectors, appearance inspection machines, container closure integrity testers, and cartoners for 2-20 mL vials. We will also consider responding to other vial sizes upon request from client companies. Moreover, we will create a cool environment for inspection and packaging operations to prevent product temperature rises.
(4) BCP in case of disaster
DynaBASE’s quake-absorbing structure and in-house power generation systems will ensure business continuity even in the event of a disaster, thereby contributing to a stable supply of pharmaceutical products.